Suicide is a leading causes of student death, especially in young men, and appears to be increasing in prevalence. The most effective preventative measures so far involve limiting access to the means of self-destruction. Institutions can monitor the built environment for ‘suicide hotspots’ such as towers, bridges and car parks, and reduce access to chemicals and drugs on campus. Social media and other online activity appear to increase the likelihood of suicide. Alcohol and recreational drugs are strong risk factors. Individuals with autism are at high risk, as are those with a diagnosis of bipolar disorder. Students who have to take time out of academic studies – or to leave – are especially vulnerable. Warning signs include social withdrawal, academic failure and low mood. Asking about suicidal thoughts appears not to increase the likelihood of suicide, but may be protective. Support pathways for distressed students and staff should be regularly reviewed. Websites should be kept updated with helpful links, including simple instructions for crisis management. Information-sharing agreements should be reviewed to consider permissions to contact next of kin. All institutions need a suicide ‘postvention’ plan and team in readiness to compassionately manage the rare but devastating occurrence of suicide.