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48 - Oocyte Donation

from PART III - ASSISTED REPRODUCTION

Published online by Cambridge University Press:  04 August 2010

By
E. Bosch,
S. Reis,
J. Domingo and
J. Remohí
Edited by
Botros R. M. B. Rizk,
Juan A. Garcia-Velasco,
Hassan N. Sallam and
Antonis Makrigiannakis
Botros R. M. B. Rizk
Affiliation:
University of South Alabama
Juan A. Garcia-Velasco
Affiliation:
Rey Juan Carlos University School of Medicine,
Hassan N. Sallam
Affiliation:
University of Alexandria School of Medicine
Antonis Makrigiannakis
Affiliation:
University of Crete
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Summary

Pregnancy rates obtained with oocyte donation (OD) are the highest when compared to any other assisted reproduction technique (ART). OD is not only the solution for many infertile couples but also a reference model for obtaining useful knowledge of the physiology of reproduction and consequently to be applied in other ART. One of the controversies regarding ovarian stimulation for in vitro fertilization (IVF) regards the impact that successive cycles could have on oocyte recovery in terms of quality and quantity of the obtained oocytes. Age of the recipient, smoking, body mass index (BMI), and endometriosis are the various factors influencing embryo implantation. Endometriosis could affect uterine receptivity through alteration of the local environment by means of endocrine and paracrine mechanisms or due to changes in immune response. Gonadotropin-releasing hormone (GnRH) analogs could have a positive effect on the physiology of endometrial cells of patients with endometriosis.

Keywords

assisted reproduction techniquebody mass indexembryo implantationendometriosisoocyte donationsmokingin vitro fertilization

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Type
Chapter
Information
Infertility and Assisted Reproduction , pp. 443 - 447
Publisher: Cambridge University Press
Print publication year: 2008

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