Women’s mental health has long been misunderstood, misrepresented and mistreated. Historically, women have been institutionalised, dismissed and subjected to clinical models that fail to account for the dynamic nature of female biology. The reliance on male-centric research and clinical guidance in mental healthcare is dated; we seek new models that incorporate and validate a woman’s experience of menstruation, menopause and other hormonal changes. Understanding the interplay between hormones and mental health, on biological, psychological and social levels, offers a vital lens through which to understand the complexity. Through explanation of the scientific underpinnings by experts in the field and real stories of women who have endured misdiagnosis, poor treatment and disability, this book exposes the consequences of neglecting to understand a woman’s hormonal experience, and the transformative potential when care is hormonally informed. We stand at the cusp of a revolution in women’s health. Emerging research and innovation promise a future where care is compassionate, evidence-based and attuned to women’s lived realities of menstruation, menopause and mental health.