In the context of their link with motivation, Chapter 6 discusses affect, pleasure, reward, wanting and liking. The theme throughout Chapter 6 is the distinction between wanting, and liking. Although they are distinct, they are interactive in that liking something feeds back to increase wanting of it. Pure ‘liking’ in the absence of ‘wanting’ is measured by the taste-reactivity test. This test can be used to evaluate the anhedonia theory of dopamine proposed by Wise (1982). Hedonic hotspots and hedonic cold spots in the brain are identified. The chapter provides evidence for non-conscious pleasures in humans. The implications of the disruption of dopaminergic neurotransmission in Parkinson’s disease are described. The chapter then has a description of the phenomenon of electrical stimulation of the brain by rats. There is a consideration of the transfer of hedonic potency of an unconditional stimulus to a conditional stimulus. Finally, conversion of aversive situation to an appetite situation is described.