Despite being a writer who was celebrate for transcending the written word to work in multiple forms of media, Burroughs remains underrecognized for his contributions to the art of cinema, especially as a screenwriter. This chapter explores the history of Burroughs’ engagement with cinema, highlighting his neglected, and unrealized, screenplays from the late 1960s and 1970s. After exploring his 1960s collaborations with Antony Balch on the cut-up films, Towers Open Fire and The Cut-Ups, this chapter traces the arc of Burroughs’ screenwriting, from his earliest film treatment, “Twilights Last Gleamings,” his closet screenplay, The Last Words of Dutch Schultz, his screen adaptation of his novel, The Wild Boys, and his screenplay, Blade Runner: A Movie. After situating these works within the changing field of American cinema in the late 1960s and 1970s, this chapter considers Burroughs’ theoretical contributions to screenwriting in his lectures on the subject at the City College of New York and Naropa College in the mid-1970s. Through this overview of Burroughs’ screenwriting and thinking, this chapter argues that Burroughs’ remains neglected for offering a valuable vision of an alternate cinema at a crucial time in American culture and history.