Vacuum: A Biography of Nothing guides readers along a 4000-year journey investigating the evolution of vacuum as a scientific and philosophical concept. The investigation spans the whole conceptual history of vacuum – from the wild speculations of antiquity and the medieval era to the twentieth century's sophisticated explorations of the subatomic universe – with the aim of answering one question: does void exist? The answer to this question has eluded thinkers throughout the ages. The book covers the most pivotal ideas in the history of vacuum by detailing the theories of ancient scholars, the discoveries made by modern experimentalists, and the emergence of the quantum vacuum as a replacement for classical physics' idea of complete nothingness. This in-depth yet accessible guide is a fascinating read for a broad, interdisciplinary audience, from physical scientists, engineers, historians, and philosophers, to students and science enthusiasts.