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Is CO2 inhalation a specific marker for panic disorder? An experimental panic model

Published online by Cambridge University Press:  18 September 2015

E. Griez
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Summary

Patients with panic disorder (PD) report a transient feeling of anxiety upon inhalation of CO2 enriched air. They rate this experience as similar to symptoms of a panic attack. This hypersensitivity has been proposed as an experimental disease model. This paper examines the validity of single breath inhalation of 35% CO2 as a model for PD.

Keywords

PanicdisorderCO2 marker experimental modelPaniekstoomisCO2 merkerexperimenteel model

Information

Type
Research Article
Information
Acta Neuropsychiatrica , Volume 8 , Issue 4 , December 1996, pp. 105 - 108
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1996

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References

Literatuur

1.Griez, E, Lousberg, H, Hout van den, MA, Molen van der, GM. CO2 vulnerability in panic disorder. Psychiat Res 1987; 20: 87–95.Google Scholar
2.Perna, G, Battaglia, M, Garberi, A, Arancio, C, Bertani, A, Bellodi, L. 35% CO2/65% 02 inhalation test in panic patients. Psychiat Res 1994;52:159–71.Google Scholar
3.Griez, E, Zandbergen, J, Lousberg, H, Hout vd, MA. Effects of Low Pulmonary CO2 on Panic Anxiety. Compr Psychiat 1988; vol 29; 5:490–7.Google Scholar
4.Zandbergen, J, Lousberg, H, Pols, H, Loof de, C, Griez, E. Hyper-carbia versus Hypercarbia in Panie Disorder. J Affect Disord 1990;18:75–81.Google Scholar
5.Griez, E, Zandbergen, J, Pols, H, Loof de, C. Response to 35% Carbon Dioxide as a Marker of Panic in Severe Anxiety. Am J Psychiat 1990; 147;6:796–7.Google Scholar
6.Papp, LA, Klein, DF, Martinez, JM, Schneier, F, Cole, R, Liebowitz, MR, Hollander, E, Fyer, AJ, Jordan, F, Gorman, JM. Diagnostic and substance specificity of carbon dioxide-induced panic. Am J Psychiat 1989;146:779–81Google Scholar
7.Verburg, C, Griez, E, Meijer, J. A 35% Carbon Dioxide challenge in Simple Phobias. Acta psychiat scand 1994; 90: 420–3.Google Scholar
8.Verburg, C, Griez, E, Meijer, J. Discriminiation between panic disorder and generalized anxiety disorder by 35% carbon dioxide challenge. Am Psychiat 1995;152:1081–3.Google Scholar
9.Perna, G, Barbini, B, Cochi, S, Bertani, A, Gasperini, M. 35% CO2 challenge in panic and mood disorders. J affect Disord 1995; 33:189–94.CrossRefGoogle ScholarPubMed
10.Perna, G. Cocchi, S, Bertani, A, Arancio, C, Bellodi, L. 35% CO2 sensitivity in healthy first degree relatives of patients with panic disorder. Am J Psychiat 1995; 152:623–5.Google Scholar
11.Pols, H, Zandbergen, J, de Loof, C, Griez, E. Attenuation of carbon dioxide-induced panic after clonazepam treatment. Acta psychiat scand 1991; 84:585–6.Google Scholar
12.Pols, H, Hauzer, R, Meijer, J, Verburg, K, Griez, E. Fluvoxamine attenuates panic unduced by 355 CO2 challange. J. clin Psychiat 1996; 57: 539–42.Google Scholar