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Antioxidants and asthma

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AALitonjua. et al. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006 Oct;84(4):903–11.

AFogarty. et al. Corticosteroid sparing effects of vitamin C and magnesium in asthma: a randomised trial. Respir Med. 2006 Jan;100(1):174–9.

HErcan. et al. Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma. J Allergy Clin Immunol. 2006 Nov;118(5):1097–104.

Published online by Cambridge University Press:  11 September 2013

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In a nutshell

Asthmatics have higher oxidative stress and lower antioxidant capacity, linked to asthma risk and severity. This may be especially relevant in early childhood, in the womb and for certain asthma-prone genotypes.

Lots of RCTs have been done, some encouraging, but not enough to allow any firm clinical recommendations.

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Type
Brief Report
Copyright
Copyright © Cambridge University Press 2007

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