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Selenium and cancer

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MG.Kibriya et al. Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions. Toxicol Lett. 2007 Mar 8;169(2):162–76.
M.Argos et al. Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. Cancer Epidemiol Biomarkers Prev. 2006 Jul;15(7):1367–75.
IA.Asfour et al. High-dose sodium selenite can induce apoptosis of lymphoma cells in adult patients with non-Hodgkin's lymphoma. Biol Trace Elem Res. 2009 Mar;127(3):200–10.

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Published online by Cambridge University Press:  11 September 2013

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In a nutshell

Selenium has potential protective effects across the whole cancer life cycle. Observational and some clinical evidence support a preventive role, but the outcome of RCTs has been mixed.

It may be that the best effect is from organic selenium in those with low baseline levels, and possibly particular selenoprotein genotypes.

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Brief Report
Information
Arbor Clinical Nutrition Updates , Volume 316 , January 2010, pp. 1 - 4
Copyright
Copyright © Cambridge University Press 2010

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References

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