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Published online by Cambridge University Press: 30 October 2001
The human brain does not use more energy than the smaller brains ofanimals of comparable corporal weight. Uniquely, human functionslocalized largely in parts of the human brain that show greatestsize increase over other animals may be mediated primarily bynonsynaptic neurotransmission, with reduced energy cost per kilogramof brain. This may affect the energetic constraints onevolution.