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Lessons on transplant survival from a successful model system

Published online by Cambridge University Press:  04 February 2010

Stacia B. Moffett
Stacia B. Moffett
Affiliation:
Department of Zoology, Washington State University, Pullman, WA 99164-4236. cooperd@wsuvm1.csc.wsu.edu
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Abstract

Studies on the snail Melampus reveal that connectivity is crucial to the survival of transplanted ganglia. Transplanted CNS ganglia can innervate targets or induce supernumerary structures. Neuron survival is optimized by the neural incorporation that occurs when a transplanted ganglion is substituted for an excised ganglion. Better provision for the trophic requirements of neurons will improve the success of mammalian fetal transplants.

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Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 18 , Issue 1: An International Journal of Current Research and Theory with Open Peer Commentary , March 1995 , pp. 63
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Copyright © Cambridge University Press 1995

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