Mazur & Booth (1998) (M&B) suggested that high testosterone (T) relates to status, dominance, and (anti-) social behaviour. However, low T also relates to status and to formal dominance. The General Trait Covariance (GTC) model predicts both relations under the assumption that high and low T modulates the genotype in ways that enforce the development of almost polar covariant patterns of body, brain, intellectual, and personality traits, irrespective of race. The precise modelling of these dose-dependent molecular body-intelligence-personality-behaviour relations requires that causes, mechanisms, and effects enjoy equal operational standing.