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Structure of the cGMP-gated channel

Published online by Cambridge University Press:  04 February 2010

Daniel D. Oprian
Daniel D. Oprian*
Affiliation:
Graduate Department of Biochemistry and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02254
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Abstract

The subunit structure of the cGMP-gated cation channel of rod photoreceptors is rapidly being defined, and in the process the mode of regulation by Ca2+-calmodulin unraveled. Intriguingly, early results suggest that additional subunits of unknown function are associated with the channel and remain to be identified.

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