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Where the rubber meets the road: The importance of implementation

Published online by Cambridge University Press:  03 September 2003

Deanna M. Barch
Affiliation:
dbarch@artsci.wustl.edu tbraver@artsci.wustl.edu http://iac.wustl.edu/~ccpweb/
Todd S. Braver
Affiliation:
dbarch@artsci.wustl.edu tbraver@artsci.wustl.edu http://iac.wustl.edu/~ccpweb/
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Abstract

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Phillips & Silverstein argue that a range of cognitive disturbances in schizophrenia result from a deficit in cognitive coordination attributable to NMDA receptor dysfunction. We suggest that the viability of this hypothesis would be further supported by explicit implementation in a computational framework that can produce quantitative estimates of the behavior of both healthy individuals and individuals with schizophrenia.

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Copyright © Cambridge University Press 2003