In this paper the notion of assemblage, as derived from the work of Gilles Deleuze, is explored in order to consider change in prehistory. An assemblage-based approach that draws on the concept of ‘vibrant matter’ is implemented as the means of understanding change. In this approach all materials are viewed as vibrant and in flux. These ideas are used to create a heterogeneous view of change where assemblages, or parts of assemblages, may change at varying speeds and rhythms and at many different scales. These ideas are explored through the case study of changing burial practices between 3000 and 1500 cal bc on the Isle of Man. I suggest that this kind of thinking allows us to study change differently, and explore the advantages of this approach for archaeology.