The defining features of developmental psychopathology concepts include attention to theunderstanding of causal processes, appreciation of the role of developmental mechanisms, andconsideration of continuities and discontinuities between normality and psychopathology.Accomplishments with respect to these issues are reviewed in relation to attachment disorders,antisocial behavior, autism, depressive disorder, schizophrenia, and intellectual development.Major research challenges remain in relation to measurement issues, comorbidity, genderdifferences, cognitive processing, nature–nurture interplay, heterotypic continuity,continuities between normal variations and disorders, developmental programming, andtherapeutic mechanisms in effective treatments.