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Antibody to streptococcal opacity factor in human sera

Published online by Cambridge University Press:  15 May 2009

W. R. Maxted,
Jean P. Widdowson and
Cherry A. M. Fraser
W. R. Maxted
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
Jean P. Widdowson
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
Cherry A. M. Fraser
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
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Summary

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Two tests are described for detecting antibody to the type-specific opacity factor (OF) of group A streptococci. This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which out-breaks due to opacity factor-producing strains of group A streptococci occurred.

In an outbreak due to streptococci of M-type 22 there was a close correspondence between the distribution of anti-OF and of bactericidal M-antibody for the type. In a smaller outbreak due to M-type 58 streptococci, however, M-antibody was detected more often than antibody of OF.

Information

Type
Research Article
Information
Journal of Hygiene , Volume 71 , Issue 1 , March 1973, pp. 35 - 42
Copyright
Copyright © Cambridge University Press 1973

References

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