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Intradermal versus subcutaneous immunization with typhoid vaccine

Published online by Cambridge University Press:  15 May 2009

S. Iwarson
Affiliation:
Department of Infectious Diseases, University of Göteborg, East Hospital, S-416 85 Göteborg, Sweden
P. Larsson
Affiliation:
Institute of Medical Microbiology, University of Göteborg, S-413 46 Göteborg, Sweden
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Summary

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Swedish nationals about to travel abroad were immunized against typhoid with a monovalent heat-inactivated vaccine which was administered intra- or subcutaneously. No major differences in serum antibody response were noted in the two groups of vaccinees as determined with direct agglutination and indirect hemagglutination techniques. As the intracutaneous route caused fewer adverse reactions this way of administration seems to be preferable.

Information

Type
Research Article
Copyright
Copyright © Cambridge University Press 1980