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A new nephritogenic streptococcus

Published online by Cambridge University Press:  15 May 2009

Eugenia Duca ,
Gr. Teodorovici ,
C. Radu ,
Alla Vîţaˇ ,
Paula Talaşman-Niculescu ,
Elisabeta Bernescu ,
C. Feldi  and
V. Roşca
Eugenia Duca
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
Gr. Teodorovici
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
C. Radu
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
Alla Vîţaˇ
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
Paula Talaşman-Niculescu
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
Elisabeta Bernescu
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
C. Feldi
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
V. Roşca
Affiliation:
Department of Microbiology, Faculty of Medicine and Pharmacy, Iaşi, Romania
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Summary

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A local milk-borne outbreak of 85 cases of sore throat with cervical lymphadenitis, a third of whom later developed acute glomerulonephritis as a complication, is described. Renal involvement was shown by Volhard's criteria, filtered fraction data and renal biopsy findings. From lymph-node biopsies from patients, from the pharyngeal exudate of patients and carriers, and from three samples of cow's milk, 16 strains of beta-haemolytic streptococci of Lancefield group C, type zooepidemicus subtype lactose-positive, were isolated.

The aetiological role of the streptococcus isolated in this outbreak was confirmed by autoserodiagnosis (precipitation tests with Lancefield's antigens and patients' sera) which in this case proved more valuable than antistreptolysin-O titration as evidence of infection.

Two of the 85 patients, 7 months after the acute phase of illness, show nephrotic oedema and hypertension as chronic sequelae.

We are pleased to express our gratitude to Dr M. T. Parker and Dr W. R. Maxted for much advice, and confirmation of our serological and biochemical findings.

Information

Type
Research Article
Information
Journal of Hygiene , Volume 67 , Issue 4 , December 1969 , pp. 691 - 698
Copyright
Copyright © Cambridge University Press 1969

References

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