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On a Dysentery Toxin and Antitoxin

Published online by Cambridge University Press:  15 May 2009

Charles Todd
Affiliation:
Senior Assistant Bacteriologist, Serum Department, Lister Institute of Preventive Medicine.
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One of the most striking points in the pathology of Bacterial Dysentery is the fact that while the bacilli are found regularly in the mesenteric glands, they are not found in the spleen or other organs, and do not occur in the blood, urine, or milk. In this respect Lentz (p. 320) points out that the disease differs markedly from the septicaemic diseases, such as typhoid, and that it must be regarded as a local infection of the intestinal mucous membrane and corresponding lymphatic glands by the bacillus, the toxin alone passing into the circulation and giving rise to the typical clinical picture, which, as in the case of cholera, gives the impression of a severe poisoning or toxaemia.

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Type
Research Article
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Copyright © Cambridge University Press 1904