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South African Typhus

Published online by Cambridge University Press:  15 May 2009

Adrianus Pijper and
Helen Dau
Adrianus Pijper
Affiliation:
From the Authors' private laboratory, Pretoria, South Africa
Helen Dau
Affiliation:
From the Authors' private laboratory, Pretoria, South Africa
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From an outbreak of very mild “typhus-like disease” in Pretoria, which strongly resembled the cases of “sporadic” or “mild” typhus occasionally occurring in that town, a virus was isolated which was studied in guinea-pigs and rabbits, and was found to belong to the typhus-group.

This virus in cross-immunity experiments with virus of South African louse-typhus and South African tick-bite fever and also in other respects behaved exactly like the typhus-like virus the authors on a previous occasion isolated from rats in a South African town where cases of “mild” or “ sporadic ” typhus have been known to occur regularly for many years.

This constitutes evidence that South African “mild” or “sporadic” typhus comes from rats and is communicated to man by rat-fleas.

In southern Africa, therefore, one has to reckon with three typhus-like diseases: tick-bite fever, flea-typhus from rats, and louse-typhus. Tick-bite fever has a primary sore, the tick-bite, as a pathognomic symptom, the other two can only be differentiated satisfactorily from one another by cross-immunity tests.

Agglutination reactions and cross-immunity tests show that South African louse-typhus and South African rat- or flea-typhus are not identical with similar diseases in other parts of the world.

Tick-bite fever is a mild typhus-like disease extending from the Cape to South Rhodesia.

The typhus-like disease of Kenya is not tick-bite fever, and seems to be identical with fièvre boutonneuse.

Information

Type
Research Article
Information
Journal of Hygiene , Volume 35 , Issue 1 , February 1935, pp. 116 - 124
Copyright
Copyright © Cambridge University Press 1935

References

Anderson, G. V. W. (1925). Kenya Med. J. 2, 42.Google Scholar
Balfour, A. (1925). Kenya Med. J. 1, 352.Google Scholar
Clearkin, P. A. (1921). Ann. Report Kenya, also (1925) Kenya Med. J. April.Google Scholar
Dickson, I. D. (1912). Thesis submitted for M.D. Edinburgh University.Google Scholar
Felix, A. (1933). Trans. Roy. Soc. Trop. Med. Hyg. 26, 365.CrossRefGoogle Scholar
Felix, A. (1933 a). Trans. Roy. Soc. Trop. Med. Hyg. 27, 147.CrossRefGoogle Scholar
Friel, R. (1932). S. Afr. Med. J. 10 Sept.Google Scholar
Gilks, J. L. (1920 and 1921). Ann. Report Kenya.Google Scholar
Gray, F. C. (1931). J. Med. Ass. S. Africa, 26 Dec.Google Scholar
Hennessey, R. S. F. (1934). E. Afr. Med. J. 9, 42.Google Scholar
Jewell, N. P. and Cormack, R. P. (1930). J. Trop. Med. Hyg. 301.Google Scholar
McNaught, J. G. (1911). J. Roy. Army Med. Corps, 16, 505, 586 (see also S. Afr. Med. Record, 24 12. 1910).Google Scholar
Nuttall, G. H. F. (1911). Parasitology, 4, 89.CrossRefGoogle Scholar
Parker, R. R. (1933). Public Health Reports, U.S. Treasury Dept. Reprint 1569.Google Scholar
Pijper, A. (1934). s. Afr. Med. J. 15, 551.Google Scholar
Pijper, A. and Dau, H. (1930). J. Trop. Med. Hyg. 93.Google Scholar
Pijper, A. and Dau, H. (1930). Brit. J. exp. Path. 11, 287.Google Scholar
Pijper, A. and Dau, H. (1931). Brit. J. exp. Path. 12, 123.Google Scholar
Pijper, A. and Dau, H. (1932). Brit. J. exp. Path. 13, 33.Google Scholar
Pijper, A. and Dau, H. (1931). J. Med. Ass. S. Africa. 22 08.Google Scholar
Pijper, A. and Dau, H. (1933). Ned. Tijdschr. v. Geneesk. 77, 2030.Google Scholar
Pijper, A. and Dau, H. (1933 a). S. Afr. Med. J. 11 11.Google Scholar
Pijper, A. and Dau, H. (1934). Ztrlbl. f. Bakt. I Abt. Orig. (in press).Google Scholar
Roberts, J. I. and Tonking, H. D. (1933). E. Afr. Med. J. 9, 310.Google Scholar
Ross, G. R. (1932). S. Afr. Med. J. 6, 453.Google Scholar
Sant', Anna J. F. (1911). Parasitology, 4, 87.CrossRefGoogle Scholar
Scroggie, F. H. (1931). J. Med. Ass. s. Africa, 26 12.Google Scholar
Tonking, H. D. (1932). E. Afr. Med. J. 6.Google Scholar
Troup, J. MacD. and Pijper, A. (1931). Lancet, 28 11.Google Scholar