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Language disturbances in schizophrenia

Published online by Cambridge University Press:  11 April 2011

Marcella Bellani,
Cinzia Perlini and
Paolo Brambilla
Marcella Bellani*
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy)Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona, Verona and University of Udine, Udine (Italy)
Cinzia Perlini
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy)Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona, Verona and University of Udine, Udine (Italy)
Paolo Brambilla
Affiliation:
Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona, Verona and University of Udine, Udine (Italy)Scientific Institute IRCCS ‘E. Medea’, Udine (Italy)
*
Address fo correspondence: Dr. M. Bellani, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona (Italy). Fax: +39-045-585.871, E-mail: marcella.bellani@univr.it
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Abstract

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Language disturbances represent a core feature of schizophrenia, affecting social interactions and quality of life. Here we summarize linguistic and pragmatic deficits and illustrate the role of brain imaging studies in delineating the neural substrates of language deficits in patients with schizophrenia.

Keywords

speechsyntaxsemanticspragmaticsprosodypsychosisbrain imaging

Information

Type
Neurobiology of Psychosis. Clinical and Psychosocial Implications
Information
Epidemiology and Psychiatric Sciences , Volume 18 , Issue 4 , December 2009, pp. 314 - 317
Copyright
Copyright © Cambridge University Press 2010

References

REFERENCES

Ackermann, H. (2008). Cerebellar contributions to speech production and speech perception: psycholinguistic and neurobiological perspectives. Trends in Neurosciences 31, 265–272.CrossRefGoogle ScholarPubMed
Aglioti, S.M. & Fabbro, F. (2006). Neuropsicologia del Linguaggio. Il Mulino: Bologna.Google Scholar
American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th ed.American Psychiatric Association: Washington.Google Scholar
Andreasen, N.C. (1979). Thought, language, and communication disorders: diagnostic significance. Archives of General Psychiatry 36, 1325–1330.CrossRefGoogle ScholarPubMed
Andreasen, N.C., Calage, C.A. & O'Leary, D.S. (2008). Theory of mind and schizophrenia: A positron emission tomography study of medication-free patients. Schizophrenia Bulletin 34, 708–719.CrossRefGoogle ScholarPubMed
Bellani, M. & Brambilla, P. (2008a). The use and meaning of the continuous performance test in schizophrenia. Epidemiologia e Psichiatria Sociale 17, 188–191.CrossRefGoogle ScholarPubMed
Bellani, M. & Brambilla, P. (2008b). Social cognition, schizophrenia and brain imaging. Epidemiologia e Psichiatria Sociale 17, 117–119.CrossRefGoogle ScholarPubMed
Bhati, M.T. (2005). The brain, language, and schizophrenia. Current Psychiatry Reports 7, 297–303.CrossRefGoogle ScholarPubMed
Brambilla, P., Cerini, R., Gasparini, A., Versace, A., Andreone, N., Vittorini, E., Barbui, C., Pelizza, L., Nosè, M., Barlocco, L., Marrella, G., Gregis, M., Tournikioti, K., David, A.S., Keshavan, M.S. & Tansella, M. (2005). Investigation of corpus callosum in schizophrenia with diffusion imaging. Schizophrenia Research 79, 201–210.CrossRefGoogle ScholarPubMed
Broca, P. (1861). Perte de la parole, ramolissement cronique et destruction partielle du lobe anterieur gauche du cerveau. Bulletin de la Société d'Anthropologie de Paris 2, 235–238.Google Scholar
Covington, M.A., He, C., Brown, C., Naçi, L., McClain, J.T., Fjordbak, B.S., Semple, J. & Brown, J. (2005). Schizophrenia and the structure of language: the linguist's view. Schizophrenia Research 77, 85–98.CrossRefGoogle ScholarPubMed
Crow, T.J. (2008). The ‘big bang’ theory of the origin of psychosis and the faculty of language. Schizophrenia Research 102, 31–52.CrossRefGoogle ScholarPubMed
DeLisi, L.E. (2001). Speech disorder in schizophrenia: review of the literature and exploration of its relation to the uniquely human capacity for language. Schizophrenia Bulletin 27, 481–496.Google Scholar
Demonet, J., Thierry, G. & Cardebat, D. (2005). Renewal of the neuro-physiology of language: functional neuroimaging. Physiological Reviews 85, 49–95.CrossRefGoogle Scholar
Dominey, P.F. & Inui, T. (2009). Cortico-striatal function in sentence comprehension: Insights from neurophysiology and modeling. Cortex 45, 1012–1018.CrossRefGoogle ScholarPubMed
Elvevåg, B., Foltz, P.W., Weinberger, D.R. & Goldberg, T.E. (2007). Quantifying incoherence in speech: An automated methodology and novel application to schizophrenia. Schizophrenia Research 93, 304–316.CrossRefGoogle ScholarPubMed
Friederici, A.D., von Cramon, Y.D. & Kotz, S.A. (2007). Role of the corpus callosum in speech comprehension: Interfacing syntax and prosody. Neuron 53, 135–145.CrossRefGoogle ScholarPubMed
Glenthoj, A., Glenthoj, B.Y., Mackeprang, T., Pagsberg, A.K., Hemmingsen, R.P., Jernigan, T.L. & Baaré, W.F. (2007). Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. Psychiatry Research 154, 199–208.CrossRefGoogle ScholarPubMed
Kircher, T.T.J., Oh, T.M., Brammer, M.J. & McGuire, P.K. (2005). Neural correlates of syntax production in schizophrenia. British Journal of Psychiatry 186, 209–214.CrossRefGoogle ScholarPubMed
Kircher, T.T.J., Leube, D.T., Erb, M., Grodd, W. & Rapp, A.M. (2007). Neural correlates of metaphor processing in schizophrenia. Neuroimage 34, 281–289.CrossRefGoogle ScholarPubMed
Leitman, D.I., Hoptman, M.J., Foxe, J.J., Saccente, E., Wylie, G.R., Nierenberg, J., Jalbrzikowski, M., Lim, K.O. & Javitt, D.C. (2007). The neural substrates of impaired prosodic detection in schizophrenia and its sensorial antecedents. American Journal of Psychiatry 164, 474–482.CrossRefGoogle ScholarPubMed
Marini, A., Spoletini, I., Rubino, I.A., Ciuffa, M., Bria, P., Martinotti, G., Banfi, G., Boccascino, R., Strom, P., Siracusano, A., Caltagirone, C. & Spalletta, G. (2008). The language of schizophrenia: An analysis of micro and macrolinguistic abilities and their neuropsychological correlates. Schizophrenia Research 105, 144–155.CrossRefGoogle ScholarPubMed
Mitchell, R.L. & Crow, T.J. (2005). Right hemisphere language functions and schizophrenia: The forgotten hemisphere? Brain 128, 963–978.CrossRefGoogle ScholarPubMed
Park, I.H., Park, H.J., Chun, J.W., Kim, E.Y., Kim, J.J. (2008). Prefrontal functional dissociation in the semantic network of patients with schizophrenia. Neuroreport 19, 1391–1395.CrossRefGoogle ScholarPubMed
Shapleske, J., Rossell, S.L., Woodruff, P.W. & David, A.S. (1999). The planum temporale: a systematic, quantitative review of its structural, functional and clinical significance. Brain Research Reviews 29, 26–49.CrossRefGoogle ScholarPubMed
Shenton, M.E., Dickey, C.C., Frumin, M. & McCarley, R.W. (2001). A review of MRI findings in schizophrenia. Schizophrenia Research 49, 1–52.CrossRefGoogle ScholarPubMed
Stowe, L.A., Haverkort, M. & Zwarts, F. (2005). Rethinking the neurological basis of language. Lingua 115, 997–1042.CrossRefGoogle Scholar
Takahashi, T., Wood, S.J., Yung, A.R., Soulsby, B., McGorry, P.D., Suzuki, M., Kawasaki, Y., Phillips, L.J., Velakoulis, D. & Pantelis, C. (2009). Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis. Archives of General Psychiatry 66, 366–376.CrossRefGoogle ScholarPubMed
Tavano, A., Sponda, S., Fabbro, F., Perlini, C., Rambaldelli, G., Ferro, A., Cerruti, S., Tansella, M. & Brambilla, P. (2008). Specific linguistic and pragmatic deficits in Italian patients with schizophrenia. Schizophrenia Research 102, 53–62.CrossRefGoogle ScholarPubMed
Vigliocco, G. (2000). Language processing: The anatomy of meaning and syntax. Current Biology 10, 78–80.CrossRefGoogle ScholarPubMed
Wernicke, C. (1874). Der aphasische Symptomencomplex. Eine psychologische Studie auf Anatomischer Basis. Cohn and Weigert: Breslau.Google Scholar
World Health Organization (1993). The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. World Health Organization: Geneva.Google Scholar