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Overdose with sustained-release lithium preparations

Published online by Cambridge University Press:  16 April 2020

B Astruc
Affiliation:
Department of Psychiatry, Caremeau Hospital, 30000Nîmes
P Petit
Affiliation:
Department of Psychopharmacology, La Colombière Hospital, 34000Montpellier, France
M Abbar
Affiliation:
Department of Psychiatry, Caremeau Hospital, 30000Nîmes
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Summary

Acute lithium intoxication is potentially lethal. Compared to conventional lithium preparations, sustained-release lithium formulations present specific problems for medical practice in the case of overdose. We report a case of intoxication with 8000 mg of sustained-release lithium carbonate preparation (Teralithe 400 LP®). Twenty-five hours after the ingestion, the patient was still asymptomatic, despite a serum level in the toxic range. After comparison of this case with reports found in the Medline database, we consider the clinical management of such cases.

Information

Type
Case Reports
Copyright
Copyright © European Psychiatric Association 1999

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