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The rate of selection advance for non-additive loci

Published online by Cambridge University Press:  14 April 2009

W. G. Hill
W. G. Hill
Affiliation:
Institute of Animal GeneticsWest Mains Road, Edinburgh, 9
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Expected changes in the gene frequency and the population mean for a quantitative trait are described for selection in a population of size N at a single locus where the favoured allele has initial frequency q0 and selective value s. Models of additive and completely dominant gene action are compared. Results are generally expressed as the half-life of the total change relative to N.

If the favoured allele is additive or recessive the half-life of the gene frequency and mean of the trait are usually reduced when q0 or Ns is increased. However, if the dominant allele is favoured the half-life of gene frequency is still generally reduced as Ns is increased, but has a minimum at low or intermediate values of q0. Since inbreeding depression and selection oppose each other when the dominant allele is favoured the response in the mean of the quantitative trait may change in direction during selection.

Information

Type
Research Article
Information
Genetics Research , Volume 13 , Issue 2 , April 1969, pp. 165 - 173
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Griffing, B. (1960). Theoretical consequences of truncation selection based on the individual phenotype. Aust. J. biol. Sci. 13, 307–343.CrossRefGoogle Scholar
Hill, W. G. (1969). On the theory of artificial selection in finite populations. Genet. Res. 13, 143–163.CrossRefGoogle ScholarPubMed
Hill, W. G. & Robertson, A. (1966). The effect of linkage on limits to artificial selection. Genet. Res. 8, 269–294.CrossRefGoogle ScholarPubMed
Hill, W. G. & Robertson, A. (1968). The effects of inbreeding at loci with heterozygote advantage. Genetics 60, (in Press).CrossRefGoogle ScholarPubMed
Kojima, K. (1961). Effects of dominance and size of population on response to mass selection. Genet. Res. 2, 177–188.CrossRefGoogle Scholar
Latter, B. D. H. (1966). The response to artificial selection due to autosomal genes of large effect. III. The effects of linkage on the rate of advance and approach to fixation in finite populations. Aust. J. biol. Sci. 19, 131–146.CrossRefGoogle Scholar
Roberts, R. C. (1966). The limits to artificial selection for body weight in the mouse. I. The limits attained in earlier experiments. Genet. Res. 8, 347–360.CrossRefGoogle ScholarPubMed
Robertson, A. (1952). The effect of inbreeding on the variation due to recessive genes. Genetics 37, 189–207.CrossRefGoogle ScholarPubMed
Robertson, A. (1960). A theory of limits in artificial selection. Proc. R. Soc. B 153, 234–249.Google Scholar