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Active Surveillance for Carbapenem-Resistant Enterobacteriaceae Using Stool Specimens Submitted for Testing for Clostridium difficile

Published online by Cambridge University Press:  10 May 2016

David B. Banach,
Jeannette Francois,
Stephanie Blash,
Gopi Patel,
Stephen G. Jenkins,
Vincent LaBombardi,
Barry N. Kreiswirth,
Arjun Srinivasan and
David P. Calfee
David B. Banach
Affiliation:
Mount Sinai School of Medicine, New York, New York
Jeannette Francois
Affiliation:
NewYork-Presbyterian Hospital, New York, New York
Stephanie Blash
Affiliation:
Mount Sinai School of Medicine, New York, New York
Gopi Patel
Affiliation:
Mount Sinai School of Medicine, New York, New York
Stephen G. Jenkins
Affiliation:
Weill Cornell Medical College, New York, New York
Vincent LaBombardi
Affiliation:
Mount Sinai School of Medicine, New York, New York
Barry N. Kreiswirth
Affiliation:
Public Health Research Institute, International Center for Public Health, University of Medicine and Dentistry of New Jersey, Newark, New Jersey
Arjun Srinivasan
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
David P. Calfee*
Affiliation:
Weill Cornell Medical College, New York, New York
*
Weill Cornell Medical College, 525 East 68th Street, Box 265, New York, NY 10065 (dpc9003@med.cornell.edu)
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Abstract

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Active surveillance to identify asymptomatic carriers of carbapenem-resistant Enterobacteriaceae (CRE) is a recommended strategy for CRE control in healthcare facilities. Active surveillance using stool specimens tested for Clostridium difficile is a relatively low-cost strategy to detect CRE carriers. Further evaluation of this and other risk factor-based active surveillance strategies is warranted.

Information

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 35 , Issue 1 , January 2014, pp. 82 - 84
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2014

Footnotes

a.

Present affiliation: Yale School of Medicine, New Haven, Connecticut

b.

Present affiliation: New York Hospital Queens, Flushing, New York

References

1. Ben-David, Maor, Y, Keller, N, et al. Potential role of active surveillance in the control of a hospital-wide outbreak of carbapenem-resistant Klebsiella pneumoniae infection. Infect Control Hosp Epidemiol 2010;31:620–626.Google Scholar
2. Centers for Disease Control and Prevention (CDC). Guidance for Control of Carbapenem-Resistant Enterobacteriaceae (CRE):2012 CRE Toolkit. Atlanta: CDC, 2012. http://www.cdc.gov/hai/pdfs/cre/CRE-guidance-508.pdf. Accessed May 22, 2013.Google Scholar
3. Schwaber, MJ, Klarfeld-Lidji, S, Navon-Venezia, S, Schwartz, D, Leavitt, A, Carmeli, Y. Predictors of carbapenem-resistant Klebsiella pneumoniae acquisition among hospitalized adults and effect of acquisition on mortality. Antimicrob Agents Chemother 2008;52:1028–1033.Google Scholar
4. Ray, AJ, Hoyen, CK, Das, SM, Eckstein, EC, Donskey, CJ. Undetected vancomycin-resistant Enterococcus stool colonization in a Veterans Affairs hospital using a Clostridium difficile-focused surveillance strategy. Infect Control Hosp Epidemiol 2002;(8):474–477.Google Scholar
5. Landman, D, Salvani, JK, Bratu, S, Quale, J. Evaluation of techniques for detection of carbapenem-resistant Klebsiella pneumoniae in stool surveillance cultures. J Clin Microbiol 2005;43:5639–5641.Google Scholar
6. Costa, D, Vinué, L, Poeta, P, et al. Prevalence of extended-spectrum beta-lactamase-producing Escherichia colt isolates in faecal samples of broilers. Vet Microbiol 2009;138:339–344.Google Scholar
7. Poirel, L, Walsh, TR, Cuvillier, V, et al. Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis 2011;70:119–123.Google Scholar
8. Kaczmarek, FM, Dib-Hajj, F, Shang, W, et al. High-level carba-penem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of bla(ACT-1) beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe. Antimicrob Agents Chemother 2006;50:3396–3406.CrossRefGoogle Scholar
9. Swaminathan, M, Sharma, S, Poliansky-Blash, S, et al. Prevalence and risk factors for acquisition of carbapenem-resistant Enterobacteriaceae in the endemic setting. Infect Control Hosp Epidemiol 2013;34(8):809–817.CrossRefGoogle Scholar
10. Patel, G, Huprikar, S, Factor, SH, Jenkins, SG, Calfee, DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:1099–1106.Google Scholar