Objectives/Goals: The Bench Program offers academically talented high school students a unique opportunity to engage in cutting-edge research. Students are paired with a UTMB graduate student or postdoc and mentored by faculty, gaining hands-on experience in a rigorous, research-focused setting. Methods/Study Population: The Bench Tutorials course is open to all Ball High students and pairs each student with a UTMB graduate or postdoctoral mentor based on scientific interests. Students commit at least four hours weekly to supervised research and instruction, totaling about 40 hours per semester. This 5.0-credit course mirrors college-level rigor, with regular lab meetings and mentorship. Students present their research at two symposiums annually, including a Year-End event. Successful completion is considered an advanced academic achievement. Results/Anticipated Results: The Bench Program continues to serve as a model biomedical training program for qualified GISD high school students. Since its start, it has enrolled over 490 students, many of whom have pursued science-related college paths. For the upcoming year, we aim to maintain a high-quality, intensive experience by enrolling around 16 students, each paired with one of 8 dedicated mentors. This structure ensures personalized guidance and hands-on research training, helping to shape the next generation of scientific leaders. Discussion/Significance of Impact: The Bench Program gives high school students hands-on research experience with UTMB scientists. It mirrors graduate-level rigor, requiring time management and independent learning. The program is expanding to reach more students through GGCTSA partnerships.