Objectives/Goals: The Dissemination, Implementation, and Continuous Quality Improvement (DICQI) team at the Wake Forest Clinical and Translational Science Institute (WF CTSI) has implemented the Translational Science Benefits Model (TSBM) to assess impact evaluation and drive excellence in translational science. Methods/Study Population: The DICQI team collaborated with the Work Force Development, Community & Stakeholder Research Engagement, and Pilot programs to implement TSBM questions into already established surveys and applications in an effort to reduce fatigue. Respondents select up to five benefits they anticipate their project impacting and provide a brief description of each. A follow-up survey is deployed at project completion to ask if the benefits were actually impacted, with space to add additional benefits if needed. The REDCap team assisted with the build, so the anticipated benefits automatically populate into the follow-up surveys, which are typically sent after one year but are project/program dependent. Results/Anticipated Results: We anticipate that by including TSBM questions into established surveys and applications, survey burden will be low and response rate will be high. These data will be used to create impact profiles and case studies. A section of our CTSI website will be dedicated to these deliverables, we will disseminate them internally, and we will submit the most compelling ones to the TSBM website. Once we have enough TSBM data gathered, we will create dashboards to display a broad evaluation of our CTSI impact. We will also use the dashboards to identify gaps in our impact and adjust pilot funding to support projects that address such gaps. Discussion/Significance of Impact: By keeping the TSBM questions brief, auto populating the follow-up survey with previous responses, and adding to existing surveys, we expect a high response rate leading to robust data for long-term evaluation, informed decision-making, and effective dissemination.