Objectives/Goals: Community-engaged research (CER) emphasizes equitable partnerships between academic and community partners, yet many lack structured training opportunities to develop the necessary knowledge and skills to engage. Recognizing this gap, we launched a co-design process to develop a CER 101 course tailored for both community members and academics. Methods/Study Population: The CER101 design process is rooted in principles of co-design. CAB members, community partners, and academics meet as part of an iterative, interactive, facilitated process to share perspectives, exchange knowledge, and co-create course content. A 2-day workshop began with a process to align visions – define the audience of the course, identify barriers to engagement with the material, and define parameters of the final product. Activities included structured discussions, brainstorming sessions, and feedback cycles. Emphasis is placed on valuing first-hand experience alongside academic expertise to ensure accessibility and relevance. Results/Anticipated Results: The co-design process will produce a CER 101 training that reflects jointly developed foundational concepts, practical strategies for building equitable community–academic partnerships, and case studies highlighting effective CER practices. Participants are expected to demonstrate improved understanding of CER principles, enhanced ability to apply tools for collaboration, and greater appreciation for both lived and academic expertise. The training will strengthen mutual trust, expand shared capacity for CER, and inform iterative refinements to ensure sustained relevance and impact within the community of practice. Discussion/Significance of Impact: In addition to resulting in the development of a CER 101 course that includes foundational concepts and practical strategies for engaging in CER, the co-design process will lead to increased mutual understanding of CER principles, enhanced appreciation for diverse forms of expertise, and strengthen trust.