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Surface biofunctionalization of materials by amine groups

Published online by Cambridge University Press:  03 March 2011

R.J. Martín-Palma,
M. Manso,
J. Pérez-Rigueiro,
J.P. García-Ruiz and
J.M. Martínez-Duart
R.J. Martín-Palma*
Affiliation:
Departamento de Física Aplicada, Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain
M. Manso
Affiliation:
Departamento de Física Aplicada, Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain
J. Pérez-Rigueiro
Affiliation:
Departamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040 Madrid, Spain
J.P. García-Ruiz
Affiliation:
Departamento de Biología Molecular, Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain
J.M. Martínez-Duart
Affiliation:
Departamento de Física Aplicada, Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain
*
a) Address all correspondence to this author. e-mail: rauljose.martin@uam.es
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Abstract

A novel deposition technique for the bio-functionalization by amine groups of surfaces of materials is presented. The process is based on the activation at high temperature of 3-aminopropyltrietoxysilane (3-APTS) molecules in vapor phase immediately before impinging on the substrate. Materials such as silicon, porous silicon, and titanium were chosen to demonstrate the validity of the process on surfaces with very different chemical properties. The effect of the activation process on the surface was evaluated by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and x-ray diffraction (XRD). In addition, the reactivity under mild reaction conditions of the functionalized surfaces was determined by using a fluorescent reagent that specifically reacts with amine groups. From the experimental results it can be concluded that the proposed activation method induces amino-group fixation on the surface of materials, ranging from semiconductors to metals and insulating materials.

Keywords

AdsorptionChemical vapor deposition (CVD)Biological

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Type
Articles
Information
Journal of Materials Research , Volume 19 , Issue 8 , August 2004, pp. 2415 - 2420
Copyright
Copyright © Materials Research Society 2004

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