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Architected mechanical designs in tissue engineering

Published online by Cambridge University Press:  12 August 2020

Zacharias Vangelatos Open the ORCID record for Zacharias Vangelatos [Opens in a new window] ,
Chenyan Wang ,
Zhen Ma  and
Costas P. Grigoropoulos
Zacharias Vangelatos
Affiliation:
Department of Mechanical Engineering, University of California, Berkeley, CA94720, USA Laser Thermal Laboratory, University of California, Berkeley, CA94720, USA
Chenyan Wang
Affiliation:
Department of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, Syracuse University, Syracuse, NY13244, USA
Zhen Ma
Affiliation:
Department of Biomedical and Chemical Engineering, Syracuse Biomaterials Institute, Syracuse University, Syracuse, NY13244, USA
Costas P. Grigoropoulos*
Affiliation:
Department of Mechanical Engineering, University of California, Berkeley, CA94720, USA Laser Thermal Laboratory, University of California, Berkeley, CA94720, USA
*
Address all correspondence to Costas P. Grigoropoulos at cgrigoro@berkeley.edu
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Abstract

The deeper comprehension of biological phenomena has led to the pursuit of designing and architecting complex biological systems. This has been incorporated through the advances in bioprinting of artificial organs and implants even at the microscale. In addition, tissue modeling has been employed to understand and prevent malfunctional and detrimental mechanisms that lead to fatal diseases. Furthermore, the endeavor to convey the mechanical properties of both scaffolds and cells has enabled the unveiling of disease modeling and regenerative medicine. This paper aims to provide a brief review of the design, modeling and characterization of conventional and architected structures employed in bioengineering.

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MRS Communications , Volume 10 , Issue 3 , September 2020 , pp. 379 - 390
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Copyright © Materials Research Society, 2020

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