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Controlling Surface Properties with Peptides: New Methods in Molecular Self-Assembly

Published online by Cambridge University Press:  15 February 2011

Troy Wilson
Affiliation:
Department of Chemistry University of California at Berkeley Berkeley, California 94720
Mark D. Bednarski
Affiliation:
Center for Advanced Materials Materials Sciences Division Lawrence Berkeley Laboratory Berkeley, California 94720
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Extract

As part of our investigation into the design and applications of proteolytic enzymes, we required a convenient method to attach peptides to the surface of a variety of materials. In this paper we report the synthesis and characterization of a class of peptide derivatized lipids (PDL's) that can be self-assembled into monomolecular films. These films can be used to control interfacial properties such as wetting and adhesion and provide a simple method to coat surfaces with amino acids.

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