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DNA Separation Using Gold/Magnetic Iron-oxide Composite Nanoparticles

Published online by Cambridge University Press:  01 February 2011

Takuya Kinoshita,
Satoshi Seino,
Yohei Otome,
Yoshiteru Mizukoshi,
Takashi Nakagawa,
Tadachika Nakayama,
Tohru Sekino,
Koichi Niihara and
Takao A. Yamamoto
Takuya Kinoshita
Affiliation:
Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Satoshi Seino
Affiliation:
Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
Yohei Otome
Affiliation:
Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Yoshiteru Mizukoshi
Affiliation:
Osaka Prefectural College of Technology, Neyagawa, Osaka 572-8572, Japan.
Takashi Nakagawa
Affiliation:
Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Tadachika Nakayama
Affiliation:
Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
Tohru Sekino
Affiliation:
Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
Koichi Niihara
Affiliation:
Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
Takao A. Yamamoto
Affiliation:
Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
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Abstract

Amounts of oligonucleotides adsorbed onto the Au/γ-Fe2O3 composite nanoparticles synthesized by gamma-ray irradiation and picked up by a magnet were evaluated using fluorescence technique. The adsorbing capacity of the oligonucleotides on our nanoparticles are larger than a commercial magnetic beads for a separation of biomolecules.

Information

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 877: Symposium S – Magnetic Nanoparticles and Nanowires , 2005, S6.30
Copyright
Copyright © Materials Research Society 2005

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