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A High-Throughput Crystallization Device to Study Biomineralization in Vitro

Published online by Cambridge University Press:  01 February 2011

Alexander Becker and
Matthias Epple
Alexander Becker
Affiliation:
Institute of Inorganic Chemistry, University of Duisburg-Essen, Universitaetsstrasse 5-7, D-45117 Essen (Germany), e-mail matthias.epple@uni-due.de
Matthias Epple
Affiliation:
Institute of Inorganic Chemistry, University of Duisburg-Essen, Universitaetsstrasse 5-7, D-45117 Essen (Germany), e-mail matthias.epple@uni-due.de
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Abstract

A new crystallization device, based on a constant-composition double-diffusion setup, was constructed to study biomineralization in vitro. The device was tested with poly(aspartic acid) as a model additive in the precipitation of calcium carbonate, showing a complete crystal growth inhibition.

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