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Measuring the microenvironmental temperature around magnetic nanoparticles

Published online by Cambridge University Press:  17 February 2014

Daniel B. Reeves
Affiliation:
Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Hall, Hanover, NH 03755, U.S.A.
John B. Weaver
Affiliation:
Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Hall, Hanover, NH 03755, U.S.A.Department of Radiology, Geisel School of Medicine, Hanover, NH 03755, U.S.A.
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Abstract

It is important to measure the temperature of magnetic nanoparticles during hyperthermia therapy to develop safe practices. We theoretically demonstrate a method for measuring the temperature of magnetic nanoparticles using induction coils and nanoparticle magnetization harmonics. A geometrically decoupled sensing coil is described that enhances the sensitivity to small amounts of iron and also could possibly be used to eliminate sensing challenges created by the high-powered hyperthermia drive field.

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