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Optical Fibers in Integrated Molecular Sensor Systems – More Than Interconnects

Published online by Cambridge University Press:  04 September 2012

Xuan Yang and
Claire Gu
Xuan Yang
Affiliation:
Department of Electrical Engineering, University of California, Santa Cruz Santa Cruz, CA 95064, U.S.A.Engineering Technologies Division, Lawrence Livermore National Laboratory, Livermore, CA 94550, U.S.A.
Claire Gu*
Affiliation:
Department of Electrical Engineering, University of California, Santa Cruz Santa Cruz, CA 95064, U.S.A.
*
* claire@soe.ucsc.edu
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Abstract

Optical fibers have been successfully used in long-haul communication, endoscopy, and other optical systems to transmit optical power as well as information from one point to another, serving as interconnects at various scales. In integrated sensor systems, optical fibers have been frequently employed to connect the source and the detector, due to their flexibility, compactness, and low loss. However, optical fibers can provide more functions than a simple transmission channel. In this paper, we review our work on optical fibers as a platform for molecular sensors based on Raman spectroscopy (RS) and surface enhanced Raman scattering (SERS). The fibers serve to significantly increase the sensitivity of RS/SERS and to facilitate the integration of a compact sensor system. We will discuss the principles of operation of various building blocks, demonstrate our recent results, and highlight some potential applications.

Keywords

fibersensorRaman spectroscopy

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References

REFERENCES

1. Agrawal, G. P., Fiber-Optic Communication Systems (Wiley, 2002).Google Scholar
2. Grattan, K.T.V. and Meggitt, B.T., Optical Fiber Sensor Technology, (Eds., Kluwer Academic Publishers, 2000).Google Scholar
3. Giallorenzi, T. G., Bucaro, J. A., Dandridge, A., Sigel, G. H. Jr., Cole, J. H., Rashleigh, S. C., and Priest, R. G., “Optical fiber sensor technology,” IEEE J. Quantum Electron. QE-18, 626-665 (1982).Google Scholar
4. Weiss, S., Science 283, 1676–1683 (1999).Google Scholar
5. Moerner, W. E. and Fromm, D. P., Rev. Sci. Instrum. 74, 3597–3619 (2003).Google Scholar
6. Kneipp, K., Kneipp, H., Itzkan, I., Dasari, R. R., and Feld, M. S., Chem. Rev. 99, 2957 (1999).Google Scholar
7. Campion, A. and Kambhampati, P., Chem. Soc. Rev. 27, 241–250 (1998).Google Scholar
8. Kneipp, K., Kneipp, H., Itzkan, I., Dasari, R. R., and Feld, M. S., J. Phys.: Condens. Matter 14, R597–R624 (2002).Google Scholar
9. Mullen, K. I. and Carron, K. T., Anal. Chem. 63, 2196–2199 (1991).Google Scholar
10. Stokes, D. L. and Vo-Dinh, T., Sens. Actuators B 69, 28 (2000).Google Scholar
11. Stokes, D. L., Chi, Z. H., and Vo-Dinh, T., Appl. Spectrosc. 58, 292 (2004).Google Scholar
12. Viets, C. and Hill, W., J. Raman Spectrosc. 31, 625 (2000).Google Scholar
13. Viets, C. and Hill, W., J. Phys. Chem. B 105, 6330 (2001).Google Scholar
14. Viets, C. and Hill, W., Sens. Actuators B 51, 92 (1998).Google Scholar
15. Zhang, Y., Gu, C., Schwartzberg, A. Am., and Zhang, J. Z., Appl. Phys. Lett. 87, 123105 (2005).Google Scholar
16. Shi, C., Yan, H., Gu, C., Ghosh, D., Seballos, L., Chen, S., and Zhang, J. Z., Appl. Phys. Lett. 92, 103107 (2008).Google Scholar
17. Yang, X., Gu, C., Qian, F., Li, Y., and Zhang, J. Z., Anal. Chem. 83, 5888–5894 (2011).Google Scholar
18. Han, X. X., Huang, G. G., Zhao, B., and Ozaki, Y., Anal. Chem. 81, 3329–3333 (2009).Google Scholar
19. Kahraman, M., Sur, I., and Culha, M., Anal. Chem. 82, 7596–7602 (2010).Google Scholar
20. Birks, T. A., Roberts, P. J., Russell, P. S. J., Atkin, D. M., and Shepherd, T. J., Electron. Lett. 31, 1941–1943 (1995).Google Scholar
21. Cregan, R. F., Mangan, B. J., Knight, J. C., Birks, T. A., Russell, P. S. J., Roberts, P. J., and Allan, D. C., Science 285, 1537–1539 (1999).Google Scholar
22. Ritari, T., Tuominen, J., Ludvigsen, H., Petersen, J. C., Sorensen, T., Hansen, T. P., and Simonsen, H. R., Opt. Express 12, 4080–4087 (2004).Google Scholar
23. Smolka, S., Barth, M., and Benson, O., Appl. Phys. Lett. 90, 111101 (2007).Google Scholar
24. Pristinski, D. and Du, H., Opt. Lett. 31, 3246–3248 (2006).Google Scholar
25. Buric, M. P., Chen, K. P., Falk, J., and Woodruff, S. D., Appl. Opt. 47, 4255–4261 (2008).Google Scholar
26. Yan, H., Liu, J., Yang, C., Jin, G., Gu, C., and Hou, L., Opt. Express 16, 8300–8305 (2008).Google Scholar
27. Amezcua-Correa, A., Yang, J., Finlayson, C. E., Peacock, A. C., Hayes, J. R., Sazio, P. J. A., Baumberg, J. J., and Howdle, S. M., Adv. Funct. Mater. 17, 2024–2030 (2007).Google Scholar
28. Oo, M. K. K., Han, Y., Martini, R., Sukhishvili, S., and Du, H., Opt. Lett. 34, 968–970 (2009).Google Scholar
29. Han, Y., Tan, S., Oo, M. K. K., Pristinski, D., Sukhishvili, S., and Du, H., Adv. Funct. Mater. 22, 2647–2651 (2010).Google Scholar
30. Zhang, Y., Shi, C., Gu, C., Seballos, L., and Zhang, J. Z., Appl. Phys. Lett. 90, 193504 (2007).Google Scholar
31. Shi, C., Lu, C., Gu, C., Tian, L., Newhouse, R., Chen, S. and Zhang, J. Z., Appl. Phys. Lett. 93, 153101 (2008).Google Scholar
32. Yang, X., Shi, C., Wheeler, D., Newhouse, R., Chen, B., Zhang, J. Z., and Gu, C., J. Opt. Soc. Am. A 27, 977–984 (2010).Google Scholar
33. Wild, S., Roglic, G., Green, A., Sicree, R., and King, H., Diabetes Care, 27, 1047–1053 (2004).Google Scholar
34. Berger, A. J., Koo, T. W., Itzkan, I., Horowitz, G., and Feld, M. S., Appl. Opt. 38, 2916–2926 (1999).Google Scholar
35. Lambert, J., Storrie-Lombardi, M., and Borchert, M., IEEE LEOS Newsletter 12, 19–22 (1998).Google Scholar
36. Yang, X., Zhang, A. Y., Wheeler, D. A., Bond, T. C., Gu, C., and Li, Y., Anal. Bioanal. Chem. 402, 687–691 (2012).Google Scholar
37. Long, D. A., Raman Spectroscopy (McGraw-Hill, 1977).Google Scholar
38. Yang, X., Tanaka, Z., Newhouse, R., Xu, Q., Chen, B., Chen, S., Zhang, J. Z., and Gu, C., Rev. Sci. Instrum. 81, 123103 (2010).Google Scholar