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Controlling Cell Growth by Nanoparticles

Published online by Cambridge University Press:  01 February 2011

Sergiy Zankovych,
Joerg Bossert,
Ines Thiele,
Klaus D. Jandt and
Liga Berzina-Cimdina
Sergiy Zankovych
Affiliation:
s.zankovych@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany, ++ 49 3641 947736, ++ 49 3641 947732
Joerg Bossert
Affiliation:
p5jobo@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Ines Thiele
Affiliation:
ines.thiele@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Klaus D. Jandt
Affiliation:
k.jandt@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Liga Berzina-Cimdina
Affiliation:
liga@ktf.rtu,lv, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
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Abstract

We report preliminary results of using nanoparticles to control cell attachment and growth. We present the way to create titanium surfaces with different roughness in a rage between 2 nm and 117 nm by using nanoparticles as a superficial layer and varying the evaporation parameters. We examined cell proliferation on titanium substrates with increased surface roughness compared to smooth titanium surface. We used nanoparticles to create a micrometer-sized lateral layout onto substrates preliminary structured by microcontact printing. We demonstrate controlled cell growth on substrates laterally structured with nanoparticles.

Keywords

biomaterialTipowder

Information

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 950: Symposium D – Biosurfaces and Biointerfaces , 2006, 0950-D04-15
Copyright
Copyright © Materials Research Society 2007

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References

REFERENCES

1. Anselme, K., Biomaterials 21(7), 667 (2000).Google Scholar
2. Buser, D., Broggini, N., Wieland, M., Schenk, R. K., Denzer, A. J., Cochran, D. L., Hoffmann, B., Lussi, A., and Steinemann, S. G., Journal of Dental Research 83(7), 529 (2004).Google Scholar
3. Cai, K. Y., Frant, M., Bossert, J., Hildebrand, G., Liefeith, K., and Jandt, K. D., Colloids and Surfaces B-Biointerfaces 50(1), 1 (1-6-2006).Google Scholar
4. Colon, G., Ward, B. C., and Webster, T. J., Journal of Biomedical Materials Research Part A 78A(3), 595 (1-9-2006).Google Scholar
5. Evis, Z., Sato, M., and Webster, T. J., Journal of Biomedical Materials Research Part A 78A(3), 500 (1-9-2006).Google Scholar
6. Germanier, Y., Tosatti, S., Broggini, N., Textor, M., and Buser, D., Clinical Oral Implants Research 17(3), 251 (2006).Google Scholar
7. Liu, D. P., Majewski, P., O'Neill, B. K., Ngothai, Y., and Colby, C. B., Journal of Biomedical Materials Research Part A 77A(4), 763 (15-6-2006).Google Scholar
8. Liu, Q., Ding, J., Mante, F. K., Wunder, S. L., and Baran, G. R., Biomaterials 23(15), 3103 (2002).Google Scholar
9. Kommireddy, D. S., Sriram, S. M., Lvov, Y. M., and Mills, D. K., Biomaterials 27(24), 4296 (2006).Google Scholar
10. Cai, K. Y., Bossert, J., and Jandt, K. D., Colloids and Surfaces B-Biointerfaces 49(2), 136 (1-5-2006).Google Scholar
11. Michel, B., Bernard, A., Bietsch, A., Delamarche, E., Geissler, M., Juncker, D., Kind, H., Renault, J. P., Rothuizen, H., Schmid, H., Schmidt-Winkel, P., Stutz, R., and Wolf, H., Ibm Journal of Research and Development 45(5), 697 (2001).Google Scholar
12. Wilbur, J. L., Kumar, A., Kim, E., and Whitesides, G. M., Advanced Materials 6(7-8), 600 (1994).Google Scholar