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Effects of Surface Texturing on Cell Adhesion for Artificial Joints

Published online by Cambridge University Press:  17 March 2011

B. Shi
Affiliation:
Department of Chemistry and Biochemistry, University of Alaska Fairbanks, Fairbanks, AK 99775
A. Fairchild
Affiliation:
Department of Mechanical Engineering, University of Alaska Fairbanks, Fairbanks, AK 99775
Z. Kleine
Affiliation:
Department of Chemistry and Biochemistry, University of Alaska Fairbanks, Fairbanks, AK 99775
T. Kuhn
Affiliation:
Department of Chemistry and Biochemistry, University of Alaska Fairbanks, Fairbanks, AK 99775
H. Liang*
Affiliation:
Department of Mechanical Engineering, University of Alaska Fairbanks, Fairbanks, AK 99775
*
*Corresponding author: ffhl@uaf.edu
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Abstract

One of the major issues of joint implants is their loss (detachment) and subsequent failure after a limited number of years in application. Understanding and improving cell adhesion to implanting materials to extend lifespan, lubrication, and self-regeneration properties are therefore substantially important. In this research, we investigate effects of surface properties, such as wettabilty and texture on cell culture for the purpose of biotribological applications. Materials used are polyurethane, polyvinyl alcohol, and glass. Surface analysis indicates that surface structures have profound impact on cells growth.

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