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Efficient Upconverting Nanophosphors for Imaging and Photodynamic Therapy

Published online by Cambridge University Press:  11 July 2012

Brian G. Yust,
Gangadharan Ajith Kumar,
Lawrence C. Mimun and
Dhiraj K. Sardar
Brian G. Yust
Affiliation:
Dept. of Physics & Astronomy, Univ. of Texas at San Antonio, One UTSA Circle, San Antonio, Tx, 78249-1644 U.S.A.
Gangadharan Ajith Kumar
Affiliation:
Dept. of Physics & Astronomy, Univ. of Texas at San Antonio, One UTSA Circle, San Antonio, Tx, 78249-1644 U.S.A.
Lawrence C. Mimun
Affiliation:
Dept. of Physics & Astronomy, Univ. of Texas at San Antonio, One UTSA Circle, San Antonio, Tx, 78249-1644 U.S.A.
Dhiraj K. Sardar
Affiliation:
Dept. of Physics & Astronomy, Univ. of Texas at San Antonio, One UTSA Circle, San Antonio, Tx, 78249-1644 U.S.A.
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Abstract

Erbium-Ytterbium codoped nanophosphor systems are explored for high efficiency upconversion. The NIR to visible upconversion from 1550 nm and 980 nm excitation are of particular interest to us for biomedical applications such as imaging, sensing, and photodynamic therapy. Variations in synthesis method and rare earth concentration are carried out in sodium, potassium, and transition metal based phosphor materials. The spectroscopic properties of the material dry and in biologically appropriate solution are taken. After bioconjugation, these particles will be used in a mouse model to demonstrate that cancer imaging with a near-infrared excitation source is possible.

Keywords

nanostructureluminescencelanthanide

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Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1471: Symposium YY – Rare-Earth-Based Materials , 2012, mrss12-1471-yy07-06
Copyright
Copyright © Materials Research Society 2012

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References

REFERENCES

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