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Engineering Biomaterials that Exhibit Recognition and Specificity

Published online by Cambridge University Press:  15 February 2011

B. D. Ratner,
T. Boland,
E. E. Johnston and
C. D. Tidwell
B. D. Ratner
Affiliation:
Center for BioengineeringDepartment of Chemical Engineering, University of Washington, Box 351750, SEATTLE, WA 98195, ratner@cheme.washington.edu
T. Boland
Affiliation:
Department of Chemical Engineering, University of Washington, Box 351750, SEATTLE, WA 98195, ratner@cheme.washington.edu
E. E. Johnston
Affiliation:
Department of Chemical Engineering, University of Washington, Box 351750, SEATTLE, WA 98195, ratner@cheme.washington.edu
C. D. Tidwell
Affiliation:
Center for Bioengineering
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Abstract

A set of methods that can be used to create surfaces to accurately control biological reactions is described. These include strategies for inhibiting non-specific reactions, making highly organized surfaces, spatially arraying recognition moieties and characterizing complex surfaces.

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