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Synthesis of Functionalized Targeted Polyamides

Published online by Cambridge University Press:  15 February 2011

P. M. Mungara and
K. E. Gonsalves
P. M. Mungara
Affiliation:
Polymer Science Program, Institute of Materials Science, U-136 & Department of Chemistry, University of Connecticut, Storrs, CT 06269
K. E. Gonsalves
Affiliation:
Polymer Science Program, Institute of Materials Science, U-136 & Department of Chemistry, University of Connecticut, Storrs, CT 06269
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Abstract

A synthetic approach to polyamides containing the tyrosine-leucine linkage is presented. The diphenyl phosphoryl azide, (DPPA), coupling technique was utilized to synthesize the monomers. Solution polymerization of monomer I, tyrosylleucyliminohexamethyleneiminoleucyltyrosine, with adipoyl and sebacoyl chlorides gave polymers with intrinsic viscosities of 0.18 dL/g and 0.13 dL/g respectively in 90% formic acid. Interfacial polymerization of the monomer yielded a fibrous crosslinked material which was found to be a poly(amide-ester) by IR spectroscopic analysis.

Information

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 330: Symposium S – Biomolecular Materials by Design , 1993, 13
Copyright
Copyright © Materials Research Society 1994

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References

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