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Time Interval and Continuous Testing of Stimuli Responsive Hydrogels

Published online by Cambridge University Press:  07 January 2014

Jeffrey S. Bates and
Jules J. Magda
Jeffrey S. Bates
Affiliation:
Department of Materials Science and Engineering, University of Utah, 122 Central Campus Drive, Room 304, Salt Lake City, UT 84112, U.S.A.
Jules J. Magda
Affiliation:
Department of Chemical Engineering, University of Utah, 50 Central Campus Drive, Room 3290, Salt Lake City, UT 84112 U.S.A.
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Abstract

Researchers have investigated hydrogels as potential materials for biological monitoring. Hydrogel compositions have been designed to respond to changes in temperature, pH, glucose concentration and ionic strength concentration. Hydrogels designed to respond to changes in environmental conditions have demonstrated their ability to respond via a swelling or shrinking action. This swelling behavior can be exploited using a variety of signal transduction methods. While this technology shows promise, the degradation of hydrogel materials has not yet been characterized with respect to the shelf life of hydrogel samples or to their use in continuous testing. A series of experiments were performed to test hydrogels stored for extended periods of time then subjected to oscillatory testing, and the results have been analyzed to determine whether hydrogels can be used for extended periods of time for biological sensing applications.

Keywords

chemical synthesision-exchange materialpolymer

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