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The cloning of schistosome genes encoding antigenic and maturation-linked polypeptides

Published online by Cambridge University Press:  23 August 2011

M. Knight
Affiliation:
Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA
A. J. G. Simpson
Affiliation:
Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA
C. Kelly
Affiliation:
Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA
S. R. Smithers
Affiliation:
Division of Parasitology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA

Extract

Schistosomiasis is a chronic debilitating disease which accounts for considerable human mortality and morbidity and is second only to malaria in its prevalence and severity. Despite several years of concentrated effort to combat the disease with molluscicides and chemotherapy, schistosomiasis is still spreading, and it is thought that 500 million people are currently exposed to infection (larotski & Davis, 1981).

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