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Basic concepts and new aspects of vaccine development

Published online by Cambridge University Press:  06 April 2009

I. M. Roitt
I. M. Roitt
Affiliation:
Department of Immunology, University College and Middlesex School of Medicine, London WI
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Abstract

I wish to thank the Society for inviting me to give the Introductory Talk in this Symposium. It is going to centre around what might be called ‘epitope specific’ immunization and I want to draw your attention to a number of factors which will be bound to affect any new approach to the development of vaccines. To begin with, it is now clear that complex antigens, such as those associated with parasites, present many different epitopes to the immune system. These epitopes are ‘seen’ by different cell types using different receptors and epitope recognition can activate a number of different effector systems.

Keywords

vaccine developmentepitope recognitionprotein engineeringB cell responsesT cell responses.

Information

Type
Research Article
Information
Parasitology , Volume 98 , supplement S1: Symposia of the British Society for Parasitology Volume 26:Vaccines and vaccination strategies , January 1989, pp. S7 - S18
Copyright
Copyright © Cambridge University Press 1989

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References

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