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Epidemiological significance of vector–parasite interactions

Published online by Cambridge University Press:  06 April 2009

C. Dye
C. Dye
Affiliation:
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
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Summary

A great deal of published experimental evidence shows that parasite-induced changes in host choice, and biting and survival rates of bloodsucking insects are an important source of bias in estimates of Vectorial Capacity. I argue here that, because of the difficulties of handling these and other biases in practice, indices (based on the Vectorial Capacity) which purport to measure transmission rate are best used in a comparative rather than an absolute way. They should attempt to measure, not transmission rate, but changes in transmission rate. In this case, the less restrictive assumption that parasites are responsible for constant bias (rather than no bias) leads to relatively small errors. The results encourage a more optimistic view of the performance of classical entomological indices such as the parous rate. They should also help to redirect the principal epidemiological question about vector–parasite interactions: future studies should be concerned with the impact of parasites, not directly on Vectorial Capacity, but on the comparative measures which are actually used to evaluate transmission rate.

Keywords

epidemiologyvector–parasite interactionsVectorial Capacity

Information

Type
Research Article
Information
Parasitology , Volume 101 , Issue 3 , December 1990, pp. 409 - 415
Copyright
Copyright © Cambridge University Press 1990

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References

REFERENCES

Anderson, R. M. (1981). Population dynamics of indirectly transmitted disease agents: the vector component. In Vectors of Disease Agents, Interactions with Plants, Animals and Man (ed. McKelvey, J. J. Jr, Eldridge, B. F. & Maramorosch, K.), pp. 13–43. New York: Praeger.Google Scholar
Armitage, P. & Berry, G. (1987). Statistical Methods in Medical Research, 2nd Edn.Oxford: Blackwell.Google Scholar
Berry, W. J., Rowley, W. A. & Christensen, B. M. (1986). Influences of developing Brugia pahangi on spontaneous flight activity of Aedes aegypti. Journal of Medical Entomology 23, 441–5.CrossRefGoogle ScholarPubMed
Birley, M. H. (1984). Estimation, tactics and disease transmission. In Pest and Pathogen Control: Strategic, Tactical and Policy Models (ed. Conway, G. R.) pp. 272–289. Chichester: John Wiley & Sons.Google Scholar
Broadbent, S. (1958). Simple mortality rates. Applied Statistics 7, 86–95.CrossRefGoogle Scholar
Clements, A. N. & Paterson, G. D. (1981). The analysis of mortality and survival rates in wild populations of mosquitoes. Journal of Applied Biology 18, 373–99.Google Scholar
Davidson, G. (1954). Estimation of the survival rate of anopheline mosquitoes in nature. Nature, London 174, 792.Google Scholar
Day, J. F., Ebert, K. M. & Edman, J. D. (1983). Feeding patterns of mosquitoes (Diptera: Culicidae) simultaneously exposed to malarious and healthy mice. Journal of Medical Entomology 20, 120–7.Google Scholar
Day, J. F. & Edman, J. D. (1983). Malaria renders mice susceptible to mosquito feeding when gametocytes are most infective. Journal of Parasitology 69, 163–70.CrossRefGoogle ScholarPubMed
Dietz, K., Molineaux, L. & Thomas, A. (1974). A malaria model tested in the African savanna. Bulletin of the World Health Organization 50, 347–57.Google Scholar
Dobson, A. P. (1988). The population biology of parasite-induced changes in host behavior. Quarterly Review of Biology 63, 139–65.Google Scholar
Dye, C. (1986). Vectorial Capacity: must we measure all its components? Parasitology Today 2, 203–9.Google Scholar
Ellrott, D. (1987). The effect of different microfilarial densities of Brugia malayi in Mastomys natalensis on the mortality of the vector Aedes aegypti. Tropical Medicine and Parasitology 38, 344.Google Scholar
Faran, M. E., Turell, M. J., Romoser, W. S., Routier, R. G., Gibbs, P. H., Cannon, T. L. & Bailey, C. L. (1987). Reduced survival of adult Culex pipiens infected with Rift Valley Fever virus. American Journal of Tropical Medicine and Hygiene 37, 403–9.Google Scholar
Garrett-Jones, C. (1964 a). Prognosis for the interruption of malaria transmission through assessment of the mosquito's Vectorial Capacity. Nature, London 204, 1173–5.CrossRefGoogle ScholarPubMed
Garrett-Jones, C. (1964 b). The human blood index of malaria vectors in relation to epidemiological assessment. Bulletin of the World Health Organization 30, 241–61.Google ScholarPubMed
Garrett-Jones, C. & Shidrawi, G. R. (1969). Malaria Vectorial Capacity of a population of Anopheles gambiae. Bulletin of the World Health Organization 40, 531–45.Google ScholarPubMed
Gillies, M. T. (1988). Anopheline mosquitoes: vector behaviour and bionomics. In Malaria: Principles and Practice of Malariology (ed. Wernsdorfer, W. H. & McGregor, I.) pp. 453–486. Edinburgh: Churchill Livingstone.Google Scholar
Golder, T. K., Otieno, L. H., Patel, N. Y. & Onyango, P. (1982). Increased sensitivity to endosulphan of Trypanosoma-infected Glossina morsitans. Annals of Tropical Medicine and Parasitology 76, 483–4.CrossRefGoogle ScholarPubMed
Golder, T. K., Otieno, L. H., Patel, N. Y. & Onyango, P. (1984). Increased sensitivity to a natural pyrethrum extract of Trypanosoma-infected Glossina morsitans. Acta Tropica 41, 77–9.Google Scholar
Kingsolver, J. G. (1987). Mosquito host choice and the epidemiology of malaria. American Naturalist 130, 811–27.Google Scholar
Klein, T. A., Harrison, B. A., Andre, R. G., Whitmire, R. E. & Inlao, I. (1982). Detrimental effects of Plasmodium cynomolgi infections on the longevity of Anopheles dirus. Mosquito News 42, 265–71.Google Scholar
Klein, T. A., Harrison, B. A., Grove, J. S., Dixon, S. V. & Andre, R. G. (1986). Correlation of survival rates of Anopheles dirus A (Diptera: Culicidae) with different infection densities of Plasmodium cynomolgi. Bulletin of the World Health Organization 64, 901–7.Google Scholar
Leake, C. J., Ussery, M. A., Nisalak, A., Hoke, C. L., Andre, R. G. & Burke, D. S. (1986). Virus isolations from mosquitoes collected during the 1982 Japanese encephalitis epidemic in northern Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 831–7.CrossRefGoogle ScholarPubMed
Macdonald, G. (1982). The analysis of equilibrium in malaria. Tropical Disease Bulletin 49, 813–29.Google Scholar
Mahon, R. & Gibbs, A. (1982). Arbovirus-infected hens attract more mosquitoes. In Viral Diseases in Southeast Asia and the Western Pacific (ed. Mackenzie, J. D.) pp. 502–504. Sydney: Academic Press.Google Scholar
Maier, W. A., Becker-Feldman, H. & Seitz, H. M. (1987). Pathology of malaria-infected mosquitoes. Parasitology Today 3, 216–18.Google Scholar
Molineaux, L. (1985). The pros and cons of modelling malaria transmission. Transactions of the Royal Society of Tropical Medicine and Hygiene 79, 743–7.Google Scholar
Molineaux, L. & Gramiccia, G. (1980). The Garki Project. Geneva: World Health Organization, Geneva.Google Scholar
Molineaux, L., Muir, D. A., Spencer, H. C. & Wernsdorfer, W. H. (1988). The epidemiology of malaria and its measurements. In Malaria: Principles and Practice of Malariology (ed. Wernsdorfer, W. H. & McGregor, I.) pp. 999–1089. Edinburgh: Churchill Livingstone.Google Scholar
Molyneux, D. H. & Jefferies, D. (1986). Feeding behaviour of pathogen-infected vectors. Parasitology 92, 721–36.Google Scholar
Najera, J. A. (1974). A critical review of the field application of a mathematical model of malaria eradication. Bulletin of the World Health Organization 50, 449–57.Google Scholar
Nedelman, J. (1984). Inoculation and recovery rates in the malaria model of Dietz, Molineaux and Thomas. Mathematical Biosciences 69, 209–33.Google Scholar
Nitcheman, S. (1988). Comparaison des longévités des glossines (Glossina morsitans morsitans Westwood, 1850) infectées par les trypanosomes (Trypanosoma Nannomonas congolense Broden, 1904) et des glossines sains. Annales de Parasitologie Humaine et Comparée 63, 163–4.Google Scholar
Olson, J. G., Reeves, W. C., Emmons, R. W. & Milby, M. M. (1979). Correlation of Culex tarsalis population indices with the incidence of St Louis encephalitis and western equine encephalomyelitis in California. American Journal of Tropical Medicine and Hygiene 28, 335–43.CrossRefGoogle ScholarPubMed
Ribeiro, J. M. C., Rossignol, P. A. & Spielman, A. (1985). Aedes aegypti: model for blood finding strategy and prediction of parasite manipulation. Experimental Parasitology 60, 118–32.CrossRefGoogle ScholarPubMed
Rossignol, P. A., Ribeiro, J. M. C., Jngery, M., Turell, M. J., Spielman, A. & Bailey, C. L. (1985). Enhanced mosquito blood-finding success on parasitemic hosts: evidence for vector-parasite mutualism. Proceedings of the National Academy of Sciences, USA 82, 7725–7.Google Scholar
Rossignol, P. A., Ribeiro, J. M. C. & Spielman, A. (1986). Increased biting rate and reduced fertility in sporozoite-infected mosquitoes. American Journal of Tropical Medicine and Hygiene 35, 277–9.Google Scholar
Rossignol, P. A. & Rossignol, A. M. (1988). Simulations of enhanced malaria transmission and host bias induced by modified vector blood location behaviour. Parasitology 97, 363–72.CrossRefGoogle ScholarPubMed
Rowland, M. & Boersma, E. (1988). Changes in the spontaneous flight activity of the mosquito Anopheles stephensi by parasitization with the rodent malaria Plasmodium yoelii. Parasitology 97, 221–7.Google Scholar
Rowland, M. W. & Lindsay, S. W. (1986). The circadian flight activity of Aedes aegypti parasitized with the filarial nematode Brugia pahangi. Physiological Entomology 11, 325–34.Google Scholar
Turell, M. J. & Bailey, C. L. (1987). Transmission studies in mosquitoes (Diptera: Culicidae) with disseminated Rift Valley Fever virus infections. Journal of Medical Entomology 24, 11–18.Google Scholar
Turell, M. J., Bailey, C. L. & Rossi, C. A. (1984). Increased mosquito feeding on Rift Valley Fever virus-infected lambs. American Journal of Tropical Medicine and Hygiene 33, 1232–8.Google Scholar
Turell, M. J., Gargan, T. P. I. & Bailey, C. L. (1985). Culex pipiens (Diptera: Culicidae) morbidity and mortality associated with Rift Valley Fever viral infection. Journal of Medical Entomology 22, 332–7.CrossRefGoogle Scholar