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Investigating over-dispersion; Moniliformis (Acanthocephala) and rats

Published online by Cambridge University Press:  06 April 2009

D. W. T. Cromptom,
A. E. Keymer and
S. E. Arnold
D. W. T. Cromptom
Affiliation:
Department of Parasitology, Molteno Institute, Downing Street, Cambridge CB2 3EE
A. E. Keymer
Affiliation:
Department of Parasitology, Molteno Institute, Downing Street, Cambridge CB2 3EE
S. E. Arnold
Affiliation:
Department of Parasitology, Molteno Institute, Downing Street, Cambridge CB2 3EE
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Summary

An analysis of the frequency distribution of numbers of Moniliformis dubius in rats of an outbred strain of Wistar origin (CFHB) and feeding ad libitum on Oxoid 41B diet, showed that over-dispersion occurred regardless of the age and sex of the rats and the infective dose given (12, 20 or 40 cystacanths/rat). Over-dispersion was also shown to be independent of variability in the age and sex of the cystacanths given. The analysis demonstrated that the over-dispersion declined as the course of the infection proceeded. As expected, parasite survival was found to be age-dependent with female worms living longer, on average, than males, and both male and female worms living longer in rats given 12 as opposed to 20 cystacanths. Possible mechanisms for generating the over-dispersion observed during this work are discussed and a tentative hypothesis, invoking host heterogeneity with regard to carbohydrate availability in the small intestine, is proposed for further experimental investigation.

Information

Type
Research Article
Information
Parasitology , Volume 88 , Issue 2 , April 1984, pp. 317 - 331
Copyright
Copyright © Cambridge University Press 1984

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