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Powder X-ray crystallography of gallium 3-hydroxy-4-pyronates

Published online by Cambridge University Press:  10 January 2013

Lawrence R. Bernstein
Lawrence R. Bernstein
Affiliation:
Terrametrix, 107 Gilbert Avenue, Menlo Park, California 94025, USA
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Abstract

Two complexes of gallium with 3-hydroxy-4-pyrones were synthesized as potential pharmaceutical compounds for oral administration. These compounds were analyzed by powder X-ray diffraction followed by computer indexing of the data. The first compound, tris(3-hydroxy-2-methyl-4-pyronato)gallium [Ga(C6H5O3)3], was found to be orthorhombic, a = 18.500(2), b = 16.948(2), c = 12.012(2) Å, V = 3766(1) Å3, Z = 8, Dm = 1.56(5), Dx = 1.570. The compound appears closely analogous to a similar compound containing Al instead of Ga, which crystallizes in space group Pbca. The second compound, tris(3-hydroxy-2-ethyl-4-pyronato)gallium [Ga(C7H7O3)3], was found to be monoclinic, a = 31.634(2), b = 8.7662(5), c = 7.8982(5) Å, β = 103.240(6)°, V = 2132.0(5) Å3, Z = 4, Dm = 1.50(5), Dx = 1.517, with a primitive space group.

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Type
Research Article
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Powder Diffraction , Volume 10 , Issue 2 , June 1995, pp. 140 - 142
Copyright
Copyright © Cambridge University Press 1995

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