Hostname: page-component-7b7567c8c-wxvwp Total loading time: 0 Render date: 2026-11-14T21:46:15.124Z Has data issue: false hasContentIssue false
  • English
  • Français

Antipsychotic dose: from research to clinical practice

Published online by Cambridge University Press:  02 January 2018

Robert Chaplin and
Sean McGuigan
Robert Chaplin*
Affiliation:
St George's Hospital, Medical School, Cranmer Terrace, London SW17 0RE
Sean McGuigan
Affiliation:
Department of Mental Health Sciences, St. George's Hospital, Medical School
*
∗Correspondence
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the 'Save PDF' action button.

A case note study of antipsychotic prescribing in an inner London hospital showed that although doses of individual drugs were below the British National Formulary limits, polypharmacy occurred in a third of cases. Multiple regression analysis showed high doses were associated with a current risk to the self or others and increasing number of previous admissions in patients with mania and treatment non-responsiveness in schizophrenia.

Information

Type
Original Papers
Information
Psychiatric Bulletin , Volume 20 , Issue 8 , August 1996, pp. 452 - 454
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Royal College of Psychiatrists, 1996

References

British Medical Association and Royal Pharmaceutical Society of Great Britain (1993) British National Formulary, no. 26. Bath: The Bath Press.Google Scholar
Foster, P. (1989) Neuroleptic equivalence. The Pharmaceutical Journal September 30, 431–432.Google Scholar
Kane, J. M. (1994) The use of higher dose antipsychotic medication: Comment on the Royal College of Psychiatrists consensus statement. British Journal of Psychiatry, 164, 431–432.CrossRefGoogle ScholarPubMed
McEvoy, J. P., Hogarty, G. E. & Steingard, S. (1991) Optimal dose of neuroleptic in acute schizophrenia. A controlled study of the neuroleptic threshold and higher haloperidol dose. Archives of General Psychiatry, 48, 739–745.CrossRefGoogle ScholarPubMed
The Royal College of Psychiatrists: Thompson, C. (1994) Consensus statement on the use of high dose antipsychotic medication. British Journal of Psychiatry, 164, 448–458.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.