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Which dose of haloperidol?

Published online by Cambridge University Press:  02 January 2018

Trudi Hilton
Affiliation:
Maudsley Hospital, London SE5 8AZ
David Taylor*
Affiliation:
Maudsley Hospital, London SE5 8AZ
Kathryn Abel
Affiliation:
Maudsley Hospital, London SE5 8AZ
*
∗Correspondence
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Although haloperidol (HAL) has been available as an antipsychotic for over 30 years, controversy still surrounds the appropriate dose in the treatment of psychosis and in particular, schizophrenia. In practice, high dose HAL (greater than 20 mg/day) continues to be prescribed, despite good reason for not doing so: the incidence of extrapyramidal side-effects (EPSE) is known to be dose-related; and compliance with treatment may be adversely affected by side-effects, especially akathisia and Parkinsonism.

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Type
Drug Information Quarterly
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Copyright © Royal College of Psychiatrists, 1996
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