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Morphine dependent behaviour in rats: some clinical implications1

Published online by Cambridge University Press:  09 July 2009

R. Kumar and
I. P. Stolerman
R. Kumar
Affiliation:
From the Department of Pharmacology, University College London
I. P. Stolerman
Affiliation:
The Maudsley Hospital, London
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Synopsis

An animal model of morphine dependence is described, in which rats learned to overcome their aversion to solutions of morphine and eventually drank such solutions in preference to water on choice trials. Selected aspects of the acquisition, maintenance, and elimination of this type of morphine dependent behaviour were studied and the findings are discussed in terms of their relevance to man.

Information

Type
Research Article
Information
Psychological Medicine , Volume 3 , Issue 2 , May 1973, pp. 225 - 237
Copyright
Copyright © Cambridge University Press 1973

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References

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