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Second messenger signalling during hormone-induced Xenopus oocyte maturation

Published online by Cambridge University Press:  26 September 2008

R. John Cork and
Kenneth R. Robinson
R. John Cork*
Affiliation:
Department of Biological Sciences, purdue University, Indiana, USA
Kenneth R. Robinson
Affiliation:
Department of Biological Sciences, purdue University, Indiana, USA
*
Dr John Cork, Department of Anatomy, LSU Medical Center, 1901 perdido street, New Orleans, LA 70112-1393, USA.
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Summary

Although much information about such processes as cell cycle control, second messenger systems, protein kinases and steroid hormone action has been collected from studies of Xenopus oocyte maturation, we still have very little idea about how the steroid hormone, progesterone, signals the resumption of meiosis from the oocyte plasma membrane. In this review we re-examine the data on second messenger systems in Xenopus oocytes and discuss some of the unresolved questions about hormone signal transduction during maturation. We outline some reasons for the contradictions in the literature and offer some suggestions for avenues of future research.

Keywords

Intracellular second messengersMembrane progesterone receptorOocyte maturationSignal transductionXenopus laevis

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Type
Article
Information
Zygote , Volume 2 , Issue 4 , November 1994, pp. 289 - 299
Copyright
Copyright © Cambridge University Press 1994

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